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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/11172

Title: Development of a Time-restricted Region-suppressed ER-SAM Beamformer and its Application to an Auditory Evoked Field Study
Authors: Wong, Daniel
Advisor: Harrison, Robert
Department: Biomedical Engineering
Keywords: beamforming
magnetoencephalography
auditory evoked field
auditory development
Issue Date: 30-Jul-2008
Abstract: This study evaluated a time-restricted region-suppressed event-related synthetic aperture magnetoencephalography (TRRS-ER-SAM) beamformer algorithm against equivalent current dipole (ECD), and event-related synthetic aperture magnetoencephalography (ER-SAM) post-processing methods for magnetoencephalography data. This evaluation was done numerically and with auditory evoked field (AEF) data elicited by binaurally presented 500 Hz tones. The TRRS-ER-SAM beamformer demonstrated robustness to noise, and the ability to handle coherent sources. The TRRS-ER-SAM algorithm was then applied to a study of N1m AEFs in 8 subjects aged 12-25 years. The study examined the effects of age, stimulus frequency, and right-sided monaural versus binaural stimulation on the N1m location, amplitude, and latency. It was found that age affected the N1m latency; stimulus frequency affected the N1m location, amplitude, and latency; and monaural versus binaural stimulation affected the N1m amplitude. In the context of these effects, the auditory pathway structure and neurophysiological changes due to maturation were discussed.
URI: http://hdl.handle.net/1807/11172
Appears in Collections:Master
Institute of Biomaterials and Biomedical Engineering - Master theses

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