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|Title: ||Development of a Time-restricted Region-suppressed ER-SAM Beamformer and its Application to an Auditory Evoked Field Study|
|Authors: ||Wong, Daniel|
|Advisor: ||Harrison, Robert|
|Department: ||Biomedical Engineering|
auditory evoked field
|Issue Date: ||30-Jul-2008|
|Abstract: ||This study evaluated a time-restricted region-suppressed event-related synthetic aperture magnetoencephalography (TRRS-ER-SAM) beamformer algorithm against equivalent current dipole (ECD), and event-related synthetic aperture magnetoencephalography (ER-SAM) post-processing methods for magnetoencephalography data. This evaluation was done numerically and with auditory evoked field (AEF) data elicited by binaurally presented 500 Hz tones. The TRRS-ER-SAM beamformer demonstrated robustness to noise, and the ability to handle coherent sources.
The TRRS-ER-SAM algorithm was then applied to a study of N1m AEFs in 8 subjects aged 12-25 years. The study examined the effects of age, stimulus frequency, and right-sided monaural versus binaural stimulation on the N1m location, amplitude, and latency. It was found that age affected the N1m latency; stimulus frequency affected the N1m location, amplitude, and latency; and monaural versus binaural stimulation affected the N1m amplitude. In the context of these effects, the auditory pathway structure and neurophysiological changes due to maturation were discussed.|
|Appears in Collections:||Master|
Institute of Biomaterials and Biomedical Engineering - Master theses
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