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History of Surgery in Canada (UWO) >
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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/17612

Title: Malignant tumors of the central nervous system associated with familial polyposis of the colon: report of two cases.
Authors: Turcot, Jacques
Despres, Jean-Paul
St. Pierre, Francois
Keywords: Jacques Turcot
Jean P Despres
Francois St Pierre
Toucot's syndrome
Familial Polyposis of the Colon
Issue Date: 1959
Publisher: Diseases of the Colon and Rectum
Citation: Turcot J, Despres JP, St. Pierre F. Malignant tumors of the central nervous system associated with familial polyposis of the colon: report of two cases. Dis Colon Rectum. 1959 Sep-Oct;2:465-8.
Description: Turcot syndrome is the association between familial adenomatous polyposis and brain tumors like medulloblastoma, malignant glioma. It was first reported by Canadian surgeon Jacques Turcot (1914- ) et al in 1959 and hence carries the first author's name.[1] The genetic basis of Turcot syndrome is uncertain.The gene most likely to be involved is APC gene in chromosome 5q.[2] However, the syndrome has been claimed to be linked to various mutations in a number of genes.
URI: http://hdl.handle.net/1807/17612
Appears in Collections:historyofsurgery.ca

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