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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/17904

Title: Changes in cortical and pallidal oscillatory activity during the execution of a sensory trick in patients with cervical dystonia
Authors: Tang, JK
Mahant, N
Cunic, D
Chen, R
Moro, E
Lang, AE
Lozano, AM
Hutchison, WD
Dostrovsky, JO
Department: Physiology
Keywords: Geste antagoniste
Basal ganglia
Electroencephalography
Wavelet analysis
Spasmodic torticollis
Issue Date: 1-Apr-2007
Publisher: Elsevier
Citation: Tang JK et al. Changes in cortical and pallidal oscillatory activity during the execution of a sensory trick in patients with cervical dystonia. Exp Neurol. 2007;204(2):845-8.
Abstract: We examined the effects of a sensory trick (SeT) on cortical EEG and globus pallidus (GP) local field potentials in four cervical dystonia patients, two of whom had an effective SeT and two who did not. The application of an effective SeT was associated with bilateral desynchronization in the 6-8 Hz and beta bands in the GP and sensorimotor cortical regions. In contrast, mimicking an SeT led to a worsening of dystonia, which was associated with desynchronization of the beta band and synchronization in the 4-6 Hz range. These preliminary findings suggest a role for 4-8 Hz frequency synchronization in the pathophysiology of dystonia.
URI: http://hdl.handle.net/1807/17904
ISSN: 0014-4886
Appears in Collections:Faculty Publications

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