test Browse by Author Names Browse by Titles of Works Browse by Subjects of Works Browse by Issue Dates of Works
       

Advanced Search
Home   
 
Browse   
Communities
& Collections
  
Issue Date   
Author   
Title   
Subject   
 
Sign on to:   
Receive email
updates
  
My Account
authorized users
  
Edit Profile   
 
Help   
About T-Space   

T-Space at The University of Toronto Libraries >
School of Graduate Studies - Theses >
Master >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/18280

Title: Sulfonyl Chlorides as Versatile Reagents for Chelate-assisted C–H Bond Functionalizations
Authors: Dimitrijevic, Elena
Advisor: Dong, Vy Maria
Department: Chemistry
Keywords: C-H bond functionalization
sulfonyl chlorides
transition metal catalysis
Issue Date: 14-Jan-2010
Abstract: Despite the great abundance of C–H bonds in readily available starting materials, their use in synthesis of functionalized molecules has been hampered by the high bond strengths, rendering them inert to common organic reagents. However, recent progress in the field has addressed this issue, enabling selective C–H bond functionalizations to be performed using catalytic transition metal mediated processes. Herein, the use of sulfonyl chlorides as versatile reagents for C–H bond functionalizations is reported. Using chelation assistance, the regioselective conversion of C–H bonds to either C–S, C–Cl or C–C bonds was achieved. The methodology development, substrate scope determination and mechanistic investigations will be discussed.
URI: http://hdl.handle.net/1807/18280
Appears in Collections:Master
Department of Chemistry - Master theses

Files in This Item:

File Description SizeFormat
Dimitrijevic_Elena_200911_msc_thesis.pdf4.33 MBAdobe PDF
View/Open

Items in T-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

uoft