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|Title: ||Outcomes of Children Receiving In-hospital Resuscitation|
|Authors: ||Ebrahim, Shanil|
|Advisor: ||Parshuram, Christopher|
|Department: ||Medical Science|
|Issue Date: ||15-Jan-2010|
|Abstract: ||Introduction: This thesis prospectively evaluated the cognitive and functional outcomes and health-related quality of life of children admitted urgently to a Pediatric Intensive Care Unit (PICU) at the Hospital for Sick Children.
Methods: The primary outcome was the Vineland Adaptive Behavioural Scale (VABS-2) measured at 1-month and secondary outcomes were health-related quality of life, daily functioning, and caregiver perceptions.
Results: 56 children and 66 caregivers were enrolled; 42 (75%) patients and 49 (74%) caregivers completed the 1-month assessment. Children in the PICU had a mean VABS-2 score of 85(+25). Daily functioning outcomes did not significantly change from baseline to 1-month. In comparison to baseline, children had significantly reduced health-related quality of life at 1-week but no significant change was found at 1-month.
Discussion: Children surviving PICU have significant cognitive morbidity and reduced health-related quality of life that is exacerbated by more intense modes of resuscitation and increasing severity of illness.|
|Appears in Collections:||Master|
Institute of Medical Science - Master theses
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