Home

Browse
Communities
& Collections

Issue Date
Author
Title
Subject

Sign on to:

My Account
authorized users

Edit Profile

Help
 Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/18844

 Title: Change in Middle Cerebral Artery Velocity over Time to an Acute and Sustained Stimulus Authors: Regan, Rosemary Advisor: Fisher, Joseph A. Department: Physiology Keywords: Cerebral Blood FlowHypercapniaBlood Pressure Issue Date: 15-Feb-2010 Abstract: Little is known of the temporal cerebral blood flow response to a chemical stimulus consisting of increased PCO2 measured over time. Currently, there is only one study suggesting multiple phases in the CBF-CO2 response. Time constants of middle cerebral artery blood velocity (MCAV) response to a change in PETCO2 have been reported to be between 3 and 99.4 s. We studied the MCAV response in 28 subjects (10 females) to a sustained +10 mmHg above baseline (10 min) acute increase of PETCO2. We found that there were three distinct MCAV response patterns among subjects. Additionally, the responses of males and females differed. These studies suggest that there are multiple overlapping mechanisms controlling the chemoresponse of cerebral blood vessels and that these mechanisms may differ between men and women. URI: http://hdl.handle.net/1807/18844 Appears in Collections: MasterDepartment of Physiology - Master theses

Files in This Item:

File Description SizeFormat
View/Open