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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/18914

Title: Intakes of Whole and Refined Grains and Dietary Fibre In Relation to Plasma Inflammatory Protein Concentrations
Authors: Masters, Rachel Cornelia
Advisor: Hanley, Anthony James Gordon
Department: Nutritional Sciences
Keywords: epidemiologic study
diabetes risk factors
cardiovascular disease risk factors
Issue Date: 15-Feb-2010
Abstract: Inflammation contributes to the etiology of type 2 diabetes (T2D) and cardiovascular disease (CVD). Therefore, it is of interest to investigate how diet relates to plasma inflammatory proteins, particularly whole grain and fibre intakes, as these factors have been associated with lower CVD and T2D risk. Only a limited number of observational studies have examined these relationships. The objective of this study was to investigate the cross-sectional relationships of whole and refined grain and dietary fibre intakes with plasma inflammatory proteins. There was a strong inverse relationship between whole grain intake and plasminogen activator inhibitor type 1 (PAI-1) (β =-0.102; SE=0.038; p=0.0077), and a positive relationship between refined grain intake and PAI-1 (β=0.076; SE=0.034; p=0.0251). Additionally, dietary fibre was related to lower concentrations of C-reactive protein (β=-0.034; SE=0.010; p=0.0008) and fibrinogen (β=-1.207; SE=0.505; p=0.0171). This research suggests that whole and refined grain and fibre intakes may influence inflammatory protein concentrations.
URI: http://hdl.handle.net/1807/18914
Appears in Collections:Master
Department of Nutritional Sciences - Master theses

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