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|Title: ||An Economic Evaluation of HIV-associated Facial Lipoatrophy Treatments: A Cost-utility Analysis|
|Authors: ||Peyasantiwong, Sirianong|
|Advisor: ||Coyte, Peter C.|
|Department: ||Health Policy, Management and Evaluation|
|Keywords: ||facial lipoatrophy|
a cost-utility analysis
|Issue Date: ||16-Feb-2010|
|Abstract: ||Introduction: Facial lipoatrophy is a stigmatizing hallmark for HIV-positive status, and can lead to poor social functioning. Information gleaned from an economic evaluation of facial lipoatrophy treatments would inform policy decision making concerning potential public insurance coverage.
Methods: A decision-analytic model was used to estimate the lifetime costs and Quality Adjusted Life Years (QALYs) gained from treatments using either poly-l-lactic or and polyalkylimide gel for HIV positive patients. Disease progression probabilities and utilities were derived from the literature. Costs were obtained from interviews with physicians and product distributors.
Findings: Incremental costs per QALY were $66,409 CAD/$57,352 CAD for poly-l-lactic acid, and $48,715 CAD/$45,457 CAD for polyalkylimide gel® (Societal perspective/Ministry of Health perspective). Sensitivity analysis did not have a significant effect on the lower incremental costs per QALY reported for polyalkylimide gel.
Conclusion: Our base-case analysis revealed that treatments using polyalkylimide gel offers lower ICUR than treatments using poly-l-lactic acid.|
|Appears in Collections:||Master|
The Institute of Health Policy, Management and Evaluation - Master theses
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