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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/20456


Title: Morphometry of Submucous and Myenteric Esophagic Plexus of Dogs Experimentally Reinfected with Trypanosoma cruzi
Issue Date: 31-Dec-2001
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 96 Num 4
Abstract: Mem Inst Oswaldo Cruz 2001, Volume 96, Number 4, pp. 545-548 Morphometry of Submucous and Myenteric Esophagic Plexus of Dogs Experimentally Reinfected with Trypanosoma cruzi Evandro MM Machado, Deolino J Camilo Júnior, Simone W Pinheiro, Edison Reis Lopes, Alexandre J Fernandes, João Carlos Pinto Dias, Sheila J Adad Code Number: oc01083 ABSTRACT: We carried out a morphometric study of the esophagus of cross-bred dogs experimentally infected or consecutively reinfected with Trypanosoma cruzi 147 and SC-1 strains, in order to verify denervation and/or neuronal hypertrophy in the intramural plexus. The animals were sacrificed in the chronic stage, 38 months after the initial infection. Neither nests of amastigotes, nor myositis or ganglionitis, were observed in all third inferior portions of esophageal rings analyzed. No nerve cell was identified in the submucous of this organ. There was no significant difference (p>0.05) between the number, maximum diameter, perimeter, or area and volume of the nerve cells of the myenteric plexus of infected and/or reinfected dogs and of the non-infected ones. In view of these results we may conclude that the 147 and SC-1 strains have little neurotropism and do not determine denervation and/or hypertrophy in the intramural esophageal plexuses in the animals studied, independent of the reinfections. KEYWORDS: Chagas disease, Trypanosoma cruzi, dog, reinfection, esophagus, myenteric plexus Copyright 2001 Mem Inst Oswaldo Cruz
URI: http://hdl.handle.net/1807/20456
Other Identifiers: http://www.bioline.org.br/abstract?id=oc01083
Rights: Copyright 2001 Fundação Oswaldo Cruz, Fiocruz
Appears in Collections:Bioline International Legacy Collection

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