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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/20547

Title: Progressive systemic sclerosis (Scleroderma), carcinoma breast and valvular heart disease: an unusual combination
Authors: Dewani, M. S.
Qadri, S. R.
Lone, M. A.
Qureshi, K. A.
Keywords: Cancer, Systemic Sclerosis, Mitral Valve
Issue Date: 31-Dec-2000
Publisher: Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
Citation: Journal of Postgraduate Medicine (ISSN: 0972-2823) Vol 46 Num 3
Abstract: Systemic sclerosis is a multi system disorder characterised by fibrosis of skin and internal organs. There are reports of relation between cancer and polymyositis/dermatomyositis, but no overall association with systemic sclerosis. Reports of the coexistence of cancer and systemic sclerosis, however, emphasise a close temporal relation in their occurrence. Cardiac involvement in the form of myocardial fibrosis and pericarditis occurs frequently in systemic sclerosis, while valvular involvement has been reported only sporadically. We report a patient, admitted for adenocarcinoma of left breast who was found to have features of systemic sclerosis, pulmonary hypertension, gangrene of toes, and stenotic mitral valve disease. The possible mechanisms of the coincidence of the three disorders are discussed.
URI: http://hdl.handle.net/1807/20547
Other Identifiers: http://www.bioline.org.br/abstract?id=jp00065
Rights: Copyright 2000 Journal of Postgraduate Medicine. Online full text also at http://www.jpgmonline.com
Appears in Collections:Bioline International Legacy Collection

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