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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/20668

Title: Clinical signs as a guide for performing HSV-PCR in correct diagnosis of herpes simplex virus encephalitis
Authors: Abbas, B. B.
Abdolvahab, A.
Gholamali, Y. P.
Roshanak, B.
Mahmood, R.
Issue Date: 31-Dec-2003
Publisher: Medknow Publications on behalf of the Neurological Society of India
Citation: Neurology India (ISSN: 0028-3886) Vol 51 Num 3
Abstract: Background: Clinical criteria (symptoms) are not reliable enough to differentiate between different causes of encephalitis. The clinical presentation of herpes simplex virus encephalitis (HSVE) is not classically constant and in such a patient, therefore, it is vital to make early diagnosis. Aims: To investigate satisfactory and crucial clinical signs as guide to perform HSV-PCR in a rapid diagnosis of herpes simplex virus encephalitis. Material and Methods: A total of 156 CSF specimens from 70 patients with clinically suspected HSVE or meningoencephalitis were tested. The criteria for cases suspected of HSVE were fever > of lymphocytes, and MRI findings could be suggested for HSV-PCR examination. Conclusion: At the first admission, a preliminary finding of at least two important clinical features mentioned above along with the pattern of CSF cell and differential counts could be sufficient to perform HSV-PCR which could ultimately result in a rapid and correct diagnosis of herpes simplex encephalitis.
URI: http://hdl.handle.net/1807/20668
Other Identifiers: http://www.bioline.org.br/abstract?id=ni03112
Rights: Copyright 2003 Neurology India. Online full text also at http://www.neurologyindia.com
Appears in Collections:Bioline International Legacy Collection

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