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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/21409

Title: The Molluscicidal Activity of Niclosamide (Bayluscide WP70®) on Melanoides tuberculata (Thiaridae), a Snail Associated with Habitats of Biomphalaria glabrata (Planorbidae)
Authors: Giovanelli, Alexandre
Coelho da Silva, Cesar Luiz Pinto Ayres
Medeiros, Luisa
Carvalho de Vasconcellos, Maurício
Keywords: molluscicide - niclosamide - Melanoides tuberculata   - Biomphalaria glabrata   - schistosomiasis
Issue Date: 31-Dec-2002
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 97 Num 5
Abstract: The aim of this study was to determine the toxicity of niclosamide (Bayluscide ®) on Melanoides tuberculata   and Biomphalaria glabrata   under laboratory conditions. The latter species is the intermediate host of Schistosoma mansoni   (Sambon 1917). M. tuberculata was successfully used as competitor of B. glabrata in biological control programs in French West Indies. Both molluscicide and biological control using M. tuberculata have proved to be successful in reducing the population density of B. glabrata . The associated use of molluscicide in this area would be an effective measure if M. tuberculata were less susceptibility to the molluscicide than B. glabrata . Three hundreds individuals each of B. glabrata and of M. tuberculata , collected in Sumidouro, State of Rio de Janeiro, were used in the experiment. The molluscs were exposed to 14 different concentrations of niclosamide as recommended by the World Health Organization. Probit analysis was used to determine the LC 50 and LC 90. The LC 50 and LC 90 values for B. glabrata were 0.077 mg/l and 0.175 mg/l, respectively and the LC 50 and LC 90 values for M. tuberculata were 0.082 mg/l and 0.221 mg/l respectively. As the lethal concentrations of niclosamide were approximately the same to both species, this could be a disadvantage when controlling B. glabrata with niclosamide in an area of M. tuberculata occurrence. It migth therefore be preferable to utilize the latex extracted from the Euphorbia splendens, which presented a much higher efficiency for B. glabrata than to M. tuberculata .
URI: http://hdl.handle.net/1807/21409
Other Identifiers: http://www.bioline.org.br/abstract?id=oc02141
Rights: Copyright 2002 - Instituto Oswaldo Cruz - Fiocruz
Appears in Collections:Bioline International Legacy Collection

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