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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/21587


Title: Molecular epidemiology of Methicillin resistant Staphylococcus aureus isolated from newborns in a hospital in Rio de Janeiro, Brazil
Authors: Loureiro, Marcio Martins
de Moraes, B. A.
Quadra, M. R. R.
Pinheiro, G. S.
Suffys, P. N.
Asensi, Marise Dutra
Keywords: newborns, nasal carriers, methicillin resistant Staphylococcus aureus, blood culture, pulsed field gel electrophoresis, hospital infection, Rio de Janeiro, Brazil
Issue Date: 31-Dec-2000
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 95 Num 6
Abstract: Methicillin resistant Staphylococcus aureus (MRSA) is an organism that is frequently transmitted in hospitals and perinatal units. The MRSA is considered a public health problem in neonatology because of its strong potential for dissemination in the wards associated with high rates of morbidity and mortality. In this study we describe the bacteriological, epidemiological and molecular characteristics of MRSA isolated from anterior nares and blood cultures of newborns hospitalized in a public maternity hospital in the city of Rio de Janeiro, Brazil. The frequency of MRSA isolated from nasal swabs of newborns was 47.8% (43/90). The genetic analysis of MRSA strains from anterior nares, showed 8 different pulsed field gel electrophoresis patterns (PFGE). Upon analysis of PFGE patterns of the 12 MRSA strains isolated from blood cultures, 8 different patterns were observed, 9 (75%) strains were genetic related to nasal secretion isolates patterns. In conclusion, our data demonstrate the importance of screening of newborns for the presence of MRSA in Brazilian hospitals and the usefulness of genetic typing of these pathogen during epidemiologic studies. This should lead to a better knowledge on the significancy and spreading of MRSA in the hospitals.
URI: http://hdl.handle.net/1807/21587
Other Identifiers: http://www.bioline.org.br/abstract?id=oc00124
Rights: Copyright 2000 Fundacao Oswaldo Cruz Fiocruz
Appears in Collections:Bioline International Legacy Collection

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