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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/22806


Title: Mosquitocidal Bacterial Toxins: Diversity, Mode of Action and Resistance Phenomena
Authors: Charles, Jean-François
Nielsen-LeRoux, Christina
Keywords: Bacillus thuringiensis, Bacillus sphaericus, Brevibacillus laterosporus, Clostridium bifermentans, toxin binding, receptor, resistance
Issue Date: 31-Dec-2000
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 95 Num s1
Abstract: Bacteria active against dipteran larvae (mosquitoes and black flies) include a wide variety of Bacillus thuringiensis and B. sphaericus strains, as well as isolates of Brevibacillus laterosporus and Clostridium bifermentans. All display different spectra and levels of activity correlated with the nature of the toxins, mainly produced during the sporulation process. This paper describes the structure and mode of action of the main mosquitocidal toxins, in relationship with their potential use in mosquito and/or black fly larvae control. Investigations with laboratory and field colonies of mosquitoes that have become highly resistant to the B. sphaericus Bin toxin have shown that several mechanisms of resistance are involved, some affecting the toxin/receptor binding step, others unknown.
URI: http://hdl.handle.net/1807/22806
Other Identifiers: http://www.bioline.org.br/abstract?id=oc00182
Rights: Copyright 2000 Fundacao Oswaldo Cruz Fiocruz
Appears in Collections:Bioline International Legacy Collection

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