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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/23123

Title: Typing and Susceptibility to Penicillin of Neisseria meningitidis Isolated from Patients in Cuba (1993-1999)
Issue Date: 31-Dec-2001
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 96 Num 4
Abstract: Mem Inst Oswaldo Cruz 2001, Volume 96, Number 4, pp. 523-525 Typing and Susceptibility to Penicillin of Neisseria meningitidis Isolated from Patients in Cuba (1993-1999) Jorge Sosa, Rafael Llanes, Daymi Guzmán, Ibrahín Quintana, Mayra Flores, Oderay Gutiérrez Code Number: oc01080 ABSTRACT: The susceptibility to penicillin of 111 Neisseria meningitidis strains was assessed by the agar-dilution procedure and serosubtypes were determined by a whole-cell enzyme-linked immunoassay using monoclonal antibodies reagents. Thirty-five isolates showed reduced sensitivity to penicillin (MIC3 0.1 mg/l and ₤ 1 mg/l) and no resistant strains were detected. The most common phenotype was B:4:P1.15 (77.5%) and a rising trend of non-typeable and non-subtypeable strains was detected. The increase in levels of minimal inhibitory concentrations of meningococci to penicillin gives cause for concern and the increase in non-typeable and non-subtypeable isolation demand the use of molecular biology techniques for their typing. KEYWORDS: Neisseria meningitidis, typing, reduced sensitivity, Cuba Copyright 2001 Mem Inst Oswaldo Cruz
URI: http://hdl.handle.net/1807/23123
Other Identifiers: http://www.bioline.org.br/abstract?id=oc01080
Rights: Copyright 2001 Fundação Oswaldo Cruz, Fiocruz
Appears in Collections:Bioline International Legacy Collection

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