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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/23591

Title: Ultrastructural Aspects of Virus Replication in One Fatal Case and Several Other Isolates from a Dengue Type 2 Outbreak in Rio de Janeiro
Authors: Barth, Ortrud Monika
Crtes, Luzia Monteiro de Castro
Lampe, Elisabeth
Filho, Jos da Costa Farias
Keywords: Flaviviridae dengue-2 virus replication ultrastructure
Issue Date: 31-Dec-1994
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 89 Num 1
Abstract: Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain. All the Brazilian isolates presented, beside the classical structured dengue virus particles, fuzzy coated virus-like particles, never observed in the referencial New Guinea C virus strain. More numerous DEN-2 virus particles, fuzzy coated virus-like particles, defective virus particles and smooth membrane structures inside the rough endoplasmic reticulum characterized the unique fatal isolate examined.
URI: http://hdl.handle.net/1807/23591
Other Identifiers: http://www.bioline.org.br/abstract?id=oc94004
Rights: Copyright 1994 Memorias do Instituto Oswaldo Cruz.
Appears in Collections:Bioline International Legacy Collection

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