test Browse by Author Names Browse by Titles of Works Browse by Subjects of Works Browse by Issue Dates of Works
       

Advanced Search
Home   
 
Browse   
Communities
& Collections
  
Issue Date   
Author   
Title   
Subject   
 
Sign on to:   
Receive email
updates
  
My Account
authorized users
  
Edit Profile   
 
Help   
About T-Space   

T-Space at The University of Toronto Libraries >
University of Toronto at Scarborough >
Bioline International Legacy Collection >
Bioline International Legacy Collection >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/24042


Title: The serological differentiation of acute and chronic schistosomiasis japonica using IgA antibody to egg antigen
Authors: Liping, Cen
Viana, L. G.
Garcia, Teresa Cristina de Melo
Rabello, Ana Lúcia Teles
Katz, Naftale
Keywords: acute and chronic schistosomiasis japonica - serological differentiation
Issue Date: 31-Dec-1996
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 91 Num 6
Abstract: Two groups of Schistosoma japonicum infected patients (acute and chronic ) and non-infected individuals were studied using IgA antibody to egg antigen (SEA) and IgG and IgM antibodies to keyhole limpet haemocyanin (KLH). The means and standard deviation of the optical density in ELISA of acute, chronic and negative groups for IgA anti-SEA were 583+/-124.7, 98.2+/-78.8 and 82.2+/-39. 3, respectively. There was a statistically significance between acute patients and chronic patients (P{0.01). The means and standard deviation of IgG and IgM antibodies to KLH were 501.5+/-150.6, 113.0+/-79.1, 28.8+/-56.3 and 413.6+/-148.5, 70.2+/-14.8, 65.3+/-45.3, respectively. The detection results of IgA to SEA compared with the IgG and IgM to KLH did not demonstrate a significant difference (P}0.01). The sensitivities of IgA to SEA and IgG and IgM antibodies to KLH for the detection of acute infection were 95.24%, 90.48% and 85.71%, respectively. Therefore, this study showed that the detection of IgA to SEA is also a useful new method for the serological differentiation of acute and chronic schistosomiasis japonica in humans.
URI: http://hdl.handle.net/1807/24042
Other Identifiers: http://www.bioline.org.br/abstract?id=oc96137
Rights: Copyright 1996 Fundacao Oswaldo Cruz
Appears in Collections:Bioline International Legacy Collection

Files in This Item:

File Description SizeFormat
oc96137.html18.7 kBHTMLView/Open

Items in T-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

uoft