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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/25604

Title: Glycemic Index and Breast Cancer Risk and Phenotype
Authors: Greenberg, Carolyn
Advisor: Martin, Lisa
Department: Nutritional Sciences
Keywords: glycemic index
breast cancer
Issue Date: 31-Dec-2010
Abstract: Ecological studies and results from our low-fat, high-carbohydrate dietary intervention trial suggest that different carbohydrates are associated with breast cancer risk in different ways. We examined the association of diet glycemic index (GI), a ranking of carbohydrate containing foods based on their blood glucose raising potential, with breast cancer risk and phenotype. GI was calculated from multiple food records from subjects in our intervention trial using a nested case-control design (220 cases, 440 controls). GI was not associated with risk of total or estrogen receptor positive breast cancer, tumor size or nodal status. GI was strongly positively associated with hormone negative breast cancer. This finding is potentially important as little is known about the etiology of hormone negative breast cancer, which has a worse prognosis than hormone positive breast cancer. However, this finding is based on a small number of cases and should be replicated in a larger sample.
URI: http://hdl.handle.net/1807/25604
Appears in Collections:Master
Department of Nutritional Sciences - Master theses

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