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Till, James E. >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/26202

Title: Sensitivity of Cells from Normal Mouse Bone Marrow to Gamma Radiation in Vitro and in Vivo
Authors: McCulloch, E. A.
Till, J. E.
Keywords: in vivo
in vitro
radiation damage
colony forming ability
marrow cells
Issue Date: Jun-1962
Publisher: Radiation Research Society
Citation: MCCULLOCH, E. A., & TILL, J. E. (1962). Sensitivity of cells from normal mouse bone marrow to gamma radiation in vitro and in vivo. Radiation Research, 16(6), 822-832.
Series/Report no.: Radiation Research Journal
Vol. 16 No. 6
Abstract: Normal mouse bone marrow contains a small population of cells with the capacity to give rise to macroscopic colonies containing differentiated hemic cells in the spleens of heavily irradiated animals. A radiation survival curve for these colony forming cells after irradiation in vitro has been published (1). However, it remained to be shown whether this survival curve is applicable to colony-forming cells irradiated under physiological conditions in the animal. In the present paper, a survival curve for the colony-forming cells irradiated in vivo is presented and compared with the in vitro survival curve. Although these two curves are very similar, a significant difference does exist between them.
Description: Originally published in vol. 16 no. 6 of Radiation Research journal. The Radiation Research Society holds all copyright to this article. The Society allows authors to deposit their own work into their institutional repository.
URI: http://www.rrjournal.org/
http://dx.doi.org/10.2307/3571281
http://hdl.handle.net/1807/26202
ISSN: 0033-7587
Appears in Collections:Till, James E.

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