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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/30561

Title: Utility Assessment of Health-related Quality of Life (HRQOL) in Colorectal Cancer Patients: A Mixed Methodology Study
Authors: Costa, Sarah E.
Advisor: Hoch, Jeffrey
Department: Health Policy, Management and Evaluation
Keywords: health services research
economic evaluation
colorectal cancer
quality adjusted life year (QALY)
Issue Date: 6-Dec-2011
Abstract: Background: Variation exists in quality of life (i.e., utility) estimates depending on the utility elicitation method utilized. Using the EQ-5D, VAS, and HUI-III, the aim of this thesis was to determine whether these measures adequately capture HRQOL in a CRC population and assess the relationship between utility estimates generated. Methods: A mixed methods study design was employed to collect health status scores and interview data from a sample of 50 CRC patients in Toronto, Ontario. Results: Mean utility scores between the EQ-5D and HUI-III were identical at 0.76 (95% CI), with an overall VAS score of 0.72 (95% CI). Conclusion: The fact that the EQ-5D and HUI-III resulted in identical mean utility scores provides assurance for future studies using these tools in CRC. However, many factors that CRC patients identify as important to their HRQOL are not captured by these instruments. These findings have implications for informing economic evaluations.
URI: http://hdl.handle.net/1807/30561
Appears in Collections:Master

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