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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/30587

Title: The Automated Detection of Changes in Cerebral Perfusion Accompanying a Verbal Fluency Task: A Novel Application of Transcranial Doppler
Authors: Faulkner, Hayley
Advisor: Chau, Tom
Department: Biomedical Engineering
Keywords: Transcranial Doppler
access technology
Brain-computer Interface
verbal fluency
cerebral blood flow
Issue Date: 7-Dec-2011
Abstract: Evidence suggests that cerebral blood flow patterns accompanying a mental activity are retained in many locked-in patients. Thus, real-time monitoring with functional transcranial Doppler (TCD) together with a specific mental task could control a brain-computer interface (BCI), thereby providing self-initiated interaction. The objective of this study was to create an automatic detection algorithm to differentiate hemodynamic responses coincident with one's performance of verbal fluency (VF) versus counting tasks. We recruited 10 healthy adults who each silently performed up to 30 VF tasks and counted between each. Both middle cerebral arteries were simultaneously imaged using TCD. Linear Discriminant Analyses (LDA) successfully differentiated between VF and both prior and post counting tasks. For every participant, LDA achieved the 70% classification accuracy sufficient for BCIs. Results demonstrate automatic detection of a VF task by TCD and warrant further investigation of TCD as a BCI.
URI: http://hdl.handle.net/1807/30587
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