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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/31273

Title: Magnetic Resonance Elastography for Measuring the Compliance of Chronic Total Occlusions
Authors: Kates, Brian S.
Advisor: Wright, Graham
Department: Biomedical Engineering
Keywords: Elastography
Chronic Total Occlusions
MRI
MR Elastography
Angioplasty
Percutaneous Coronary Intervention
Issue Date: 12-Dec-2011
Abstract: Percutaneous coronary revascularization of chronic total occlusions (CTOs) is difficult due to the presence of a hard proximal fibrous cap and lack of image guidance. The use of x-ray fluoroscopy alone makes it difficult to identify vessel boundaries and occlusive constituents which would aid the process of revascularization. It also can be difficult to keep a guidewire intraluminal without puncturing the vessel wall. Although several imaging modalities are being developed, a technique for measuring the stiffness of occlusions would facilitate revascularization by helping the process of guidewire selection and placement. In this study, a technique known as static magnetic resonance elastography is explored as a method of determining the compliance of CTOs. A finite element simulation was used to determine the response of an artery to deformation, and displacement images were obtained from an artery phantom using a stimulated echo MR imaging pulse sequence and a pneumatic compression system.
URI: http://hdl.handle.net/1807/31273
Appears in Collections:Master

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