test Browse by Author Names Browse by Titles of Works Browse by Subjects of Works Browse by Issue Dates of Works

Advanced Search
& Collections
Issue Date   
Sign on to:   
Receive email
My Account
authorized users
Edit Profile   
About T-Space   

T-Space at The University of Toronto Libraries >
School of Graduate Studies - Theses >
Master >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/31466

Title: A Systematic Review on the use of Dexmedetomidine as a Sole Agent for Intravenous Moderate Sedation
Authors: Toong, Samuel Y.
Advisor: Haas, Daniel
Department: Dentistry
Keywords: Dexmedetomidine
Issue Date: 20-Dec-2011
Abstract: Intravenous administration of benzodiazepines can be used for anxiety management in dentistry. The recent approval of Dexmedetomidine in Canada provides an alternative to benzodiazepines for moderate sedation. There is no review comparing Dexmedetomidine and Midazolam as a sole agent for intravenous moderate sedation. This paper determines to fill the void of knowledge. A total of 6 articles out of 117 were identified in Pubmed and Ovid Medline using the key terms “Dexmedetomidine” and “sedation”. The parameters that were evaluated were the need for rescue, patient and surgeon satisfaction, and adverse outcomes. Dexmedetomidine was found to be equal or better than Midazolam in the first three parameters. Hypotension and bradycardia were evident in moderate to high doses, but none needing intervention. Other side effects include headache and dry mouth. Dexmedetomidine is a reasonable and safe alternative to Midazolam, but more research is needed to evaluate Dexmedetomidine for general dentistry.
URI: http://hdl.handle.net/1807/31466
Appears in Collections:Master

Files in This Item:

File Description SizeFormat
Toong_Samuel_Y_201111_MSc_thesis.pdf277.53 kBAdobe PDF

This item is licensed under a Creative Commons License
Creative Commons

Items in T-Space are protected by copyright, with all rights reserved, unless otherwise indicated.