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|Title: ||Patients’ Preferences and Trade Offs for the Treatment of Small Hepatocellular Carcinomas|
|Authors: ||Molinari, Michele|
|Advisor: ||Urbach, David Robert|
|Department: ||Health Policy, Management and Evaluation|
|Keywords: ||Hepatocellular Carcinoma|
|Issue Date: ||23-Jul-2012|
|Abstract: ||Objective: The primary aim of this study was to assess patients’ preferences between radiofrequency ablation (RFA) versus hepatic resection (HR) for the treatment of small hepatocellular carcinomas (HCC).
Methods: Decision analysis was performed by using probability trade-off (PTO) technique to elicit patients’ preferences and the strength of their decisions.
Results: The vast majority of the study population preferred RFA over HR (70% vs. 30%, p=0.001). Their initial choice changed if 5-year survival benefit after surgery was at least 14% superior to RFA and if the 3-year disease-free survival advantage was at least 13% better than ablation.
Conclusions: The results of this study suggest that fully informed cirrhotic patients would prefer RFA if diagnosed with early stage HCC even if able to undergo surgery.|
|Appears in Collections:||Master|
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