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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/33456

Title: Evaluation of Oral Neutrophil Levels as a Quantitative Measure of Periodontal Inflammatory Load in Patients with Special Needs
Authors: Moosani, Anita
Advisor: Sigal, Michael
Tenenbaum, Howard
Department: Dentistry
Keywords: neutrophil
periodontal disease
special needs
inflammatory load
quantification
oral swab
gingival inflammation
diagnostics
hospital dentistry
Issue Date: 22-Nov-2012
Abstract: Purpose: To validate and assess the feasibility of using an assay of oral neutrophils to measure periodontal inflammation in uncooperative patients with special needs. Methods: Periodontal examination and neutrophil counts derived from oral swabs were performed on patients with special needs having comprehensive dental treatment under general anaesthesia (GA). The conventional periodontal measurements were compared to neutrophil levels while patients were under GA, and later at their recall examination. Results: Forty-nine patients were assessed under GA and 30 (61%) returned for recall examination. Spearman’s correlation allowed for comparisons between periodontal parameters and oral neutrophil counts. Despite limited cooperation, it was possible to acquire neutrophils (using swabs) for all patients that presented for recall examination in the ambulatory dental clinic. Conclusions: Oral neutrophil levels correlated significantly with conventional parameters of gingival inflammation and may serve as a standardized method for clinical assessment of periodontal diseases in the special needs population.
URI: http://hdl.handle.net/1807/33456
Appears in Collections:Master

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