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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/33502

Title: Transcriptome Assembly and Molecular Evolutionary Analysis of Sex-biased Genes in Caenorhabditis Species 9 and Caenorhabditis Species 5
Authors: Rajagopalan, Deepthi
Advisor: Cutter, Asher
Department: Ecology and Evolutionary Biology
Keywords: Molecular evolution
Bioinformatics
Issue Date: 26-Nov-2012
Abstract: Differential gene expression between sexes is the main contributor of the morphological and behavioral differences observed between them. Studying the signatures of these differences at the genetic level will help us understand the forces acting on them. The existence of androdioecious and gonochoristic species in the genus Caenorhabditis makes it suitable for sex-biased gene expression studies. In this thesis, I have assembled the transcriptome of C. sp. 9 and C. sp. 5 using de novo and reference-based techniques. Evolutionary analysis of the assembled contigs showed that genes with male-biased expression evolve faster than those with a female bias, as observed in other taxa. Furthermore, I found a positive correlation between gene expression and codon usage bias.
URI: http://hdl.handle.net/1807/33502
Appears in Collections:Master

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