test Browse by Author Names Browse by Titles of Works Browse by Subjects of Works Browse by Issue Dates of Works
       

Advanced Search
Home   
 
Browse   
Communities
& Collections
  
Issue Date   
Author   
Title   
Subject   
 
Sign on to:   
Receive email
updates
  
My Account
authorized users
  
Edit Profile   
 
Help   
About T-Space   

T-Space at The University of Toronto Libraries >
Journal of Medical Internet Research >
Volume 7 (2005) >

Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/4739


Title: The Internet and Clinical Trials: Background, Online Resources, Examples and Issues
Authors: Paul, James
Seib, Rachael
Prescott, Todd
Keywords: Tutorial
Clinical trials
randomized controlled trial
Internet
Issue Date: 16-Mar-2005
Publisher: Gunther Eysenbach; Centre for Global eHealth Innovation, Toronto, Canada
Citation: James Paul, Rachael Seib, Todd Prescott. The Internet and Clinical Trials: Background, Online Resources, Examples and Issues. J Med Internet Res 2005;7(1):e5 <URL: http://www.jmir.org/2005/1/e5/>
Abstract: [This item is a preserved copy and is not necessarily the most recent version. To view the current item, visit http://www.jmir.org/2005/1/e5/ ] : Both the Internet and clinical trials were significant developments in the latter half of the twentieth century: the Internet revolutionized global communications and the randomized controlled trial provided a means to conduct an unbiased comparison of two or more treatments. Large multicenter trials are often burdened with an extensive development time and considerable expense, as well as significant challenges in obtaining, backing up and analyzing large amounts of data. Alongside the increasing complexities of the modern clinical trial has grown the power of the Internet to improve communications, centralize and secure data as well as to distribute information. As more and more clinical trials are required to coordinate multiple trial processes in real time, centers are turning to the Internet for the tools to manage the components of a clinical trial, either in whole or in part, to produce lower costs and faster results. This paper reviews the historical development of the Internet and the randomized controlled trial, describes the Internet resources available that can be used in a clinical trial, reviews some examples of online trials and describes the advantages and disadvantages of using the Internet to conduct a clinical trial. We also extract the characteristics of the 5 largest clinical trials conducted using the Internet to date, which together enrolled over 26000 patients.
Description: Reviewer: Marks, Ron
URI: http://hdl.handle.net/1807/4739
ISSN: 1438-8871
Other Identifiers: doi:10.2196/jmir.7.1.e5
Rights: Copyright (cc) Retained by author(s) under a Creative Commons License: http://creativecommons.org/licenses/by/2.0/
Appears in Collections:Volume 7 (2005)

Files in This Item:

File Description SizeFormat
jmir.html85.78 kBHTMLView/Open

Items in T-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

uoft