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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/5641

Title: Cutaneous manifestations in patients with chronic renal failure on hemodialysis
Authors: Udayakumar, P.
Balasubramanian, S.
Ramalingam, K. S.
Lakshmi, Chembolli
Srinivas, C. R.
Mathew, Anil C.
Keywords: Chronic renal failure, Hemodialysis
Issue Date: 31-Dec-2006
Publisher: Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
Citation: Indian Journal of Dermatology, Venereology and Leprology (ISSN: 0378-6323) Vol 72 Num 2
Abstract: Background: Chronic renal failure (CRF) presents with an array of cutaneous manifestations. Newer changes are being described since the advent of hemodialysis, which prolongs the life expectancy, giving time for these changes to manifest. Aim: The aim of this study was to evaluate the prevalence of dermatologic problems among patients with chronic renal failure (CRF) undergoing hemodialysis. Methods: One hundred patients with CRF on hemodialysis were examined for cutaneous changes. Results: Eighty-two per cent patients complained of some skin problem. However, on examination, all patients had at least one skin lesion attributable to CRF. The most prevalent finding was xerosis (79%), followed by pallor (60%), pruritus (53%) and cutaneous pigmentation (43%). Other cutaneous manifestations included Kyrle's disease (21%); fungal (30%), bacterial (13%) and viral (12%) infections; uremic frost (3%); purpura (9%); gynecomastia (1%); and dermatitis (2%). The nail changes included half and half nail (21%), koilonychia (18%), onychomycosis (19%), subungual hyperkeratosis (12%), onycholysis (10%), splinter hemorrhages (5%), Mees' lines (7%), Muehrcke's lines (5%) and Beau's lines (2%). Hair changes included sparse body hair (30%), sparse scalp hair (11%) and brittle and lusterless hair (16%). Oral changes included macroglossia with teeth markings (35%), xerostomia (31%), ulcerative stomatitis (29%), angular cheilitis (12%) and uremic breath (8%). Some rare manifestations of CRF like uremic frost, gynecomastia and pseudo-Kaposi's sarcoma were also observed. Conclusions: CRF is associated with a complex array of cutaneous manifestations caused either by the disease or by treatment. The commonest are xerosis and pruritus and the early recognition of cutaneous signs can relieve suffering and decrease morbidity.
URI: http://hdl.handle.net/1807/5641
Other Identifiers: http://www.bioline.org.br/abstract?id=dv06037
Rights: Copyright 2006 Indian Journal of Dermatology, Venereology and Leprology.
Appears in Collections:Bioline International Legacy Collection

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