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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/6600

Title: Review - Potential of probiotics as biotherapeutic agents targeting the innate immune system
Authors: Oyetayo, V.O.
Oyetayo, F.L.
Keywords: Probiotics, biotherapy, Lactic acid bacteria, immunostimulation, CpG DNA.
Issue Date: 31-Dec-2005
Publisher: Academic Journals
Citation: African Journal of Biotechnology (ISSN: 1684-5315) Vol 4 Num 2
Abstract: Probiotics had been of interest in the promotion of good health in animals and man. Some of the positive effects of probiotics are: growth promotion of farm animals, protection of host from intestinal infections, alleviation of lactose intolerance, relief of constipation, anticarcinogenic effect, anticholesterolaemic effects, nutrient synthesis and bioavailability, prevention of genital and urinary tract infections, and immunostimulatory effects. Their beneficial effects may be mediated by direct antagonism of specific groups of organisms, resulting in a decrease in numbers or by an effect on their metabolism or by stimulation of immunity. The resistance of people in developing countries to diseases can be improved upon by promoting the consumption of locally fermented foods that are rich in probiotic organisms. This article reviews the potential of probiotics as immuno-enhancing agents and the future perspective in developing potent probiotics with immunostimulatory molecules that can serve as outstanding vaccine adjuvants.
URI: http://hdl.handle.net/1807/6600
Other Identifiers: http://www.bioline.org.br/abstract?id=jb05023
Rights: Copyright 2005 - Academic Journals
Appears in Collections:Bioline International Legacy Collection

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