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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/7148

Title: Role of pre-operative dexamethasone as prophylaxis for postoperative nausea and vomiting in laparoscopic surgery
Authors: Gupta, P.
Khanna, J.
Mitramustafi, A. K.
Bhartia, V. K.
Keywords: Laparoscopic surgery, steroids, preoperative dexamethasone, postoperative nausea and vomiting.
Issue Date: 31-Dec-2006
Publisher: Medknow Publications
Citation: Journal of Minimal Access Surgery (ISSN: 0972-9941) Vol 2 Num 1
Abstract: Introduction: Laparoscopic surgery provides tremendous benefits to patients, including faster recovery, shorter hospital stay and prompt return to normal activities. Despite the minimally invasive nature of laparoscopy, high incidence of postoperative nausea and vomiting remains a major cause for morbidity. The aim of the present study was to investigate whether preoperative Dexamethasone can reduce PONV in patients undergoing laparoscopic Surgery. Materials and Methods: The study included 200 patients undergoing laparoscopic cholecystectomy. We divided the patients into two groups; one group received preoperative Dexamethasone (group 1) and the other group received Ondansetron (group 2). After surgery, patients were observed for any episode of nausea or vomiting, or whether the patient required any anti-emetic drug in the postoperative period. Results: The two groups, (Dexamethasone and Ondansetron) were comparable in outcome, in terms of post-operative nausea and vomiting, in patients undergoing laparoscopic cholecystectomy. In group I, 24% of patients had nausea, as compared to 30% in group II ( P =0.2481). Similarly, 12% of patients in group I and 18% of patients in group II had vomiting ( P =0.3574). Conclusion: We conclude that, preoperative intravenous low dose Dexamethasone reduces the incidence of PONV and is comparable to intravenous Ondansetron.
URI: http://hdl.handle.net/1807/7148
Other Identifiers: http://www.bioline.org.br/abstract?id=ma06003
Rights: Copyright 2006 Journal of Minimal Access Surgery.
Appears in Collections:Bioline International Legacy Collection

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