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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/7447

Title: Oxidants and antioxidants in human fertility
Authors: Agarwal, Ashok
Allamaneni, Shyam S.R.
Keywords: Oxidants, antioxidants, infertility - male & female, spermatozoa, reactive oxygen species, free radicals.
Issue Date: 31-Dec-2004
Publisher: Middle East Fertility Society
Citation: Middle East Fertility Society Journal (ISSN: 1110-5690) Vol 9 Num 3
Abstract: Oxidants are highly unstable molecules that attack every chemical substance they come into contact. Oxidants modify the macromolecules both structurally and functionally. Body has defense mechanisms against oxidants in the form of both enzymatic and non-enzymatic antioxidants. Reactive oxygen species (ROS) are a group of oxidants formed during oxygen metabolism. ROS appears to be involved in the pathogenesis of many human diseases. In reproductive medicine, ROS have both physiological and pathological role in male and female reproduction. Oxidative stress develops when the generation of ROS overwhelms the scavenging capacity of antioxidants. Oxidative stress causes damage to spermatozoa, oocyte and embryos. It appears to play a role in both natural and in vitro fertilization and pregnancy. The patients with oxidative stress may benefit from the strategies to reduce oxidative stress and treatment with antioxidants.
URI: http://hdl.handle.net/1807/7447
Other Identifiers: http://www.bioline.org.br/abstract?id=mf04034
Rights: Copyright 2004 - Middle East Fertility Society
Appears in Collections:Bioline International Legacy Collection

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