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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/7525

Title: Cell targeting in anti-cancer gene therapy
Authors: Lila, Mohd Azmi Mohd
Siew, John Shia Kwong
Zakaria, Hayati
Saad, Suria Mohd
Ni, Lim Shen
Abdullah, Jafri Malin
Keywords: Gene therapy, anti-cancer, cell targeting, apoptosis
Issue Date: 31-Dec-2004
Publisher: School of Medical Sciences, Universiti Sains Malaysia
Citation: Malaysian Journal of Medical Sciences (ISSN: 1394-195X) Vol 11 Num 1
Abstract: Gene therapy is a promising approach towards cancer treatment. The main aim of the therapy is to destroy cancer cells, usually by apoptotic mechanisms, and preserving others. However, its application has been hindered by many factors including poor cellular uptake, non-specific cell targeting and undesirable interferences with other genes or gene products. A variety of strategies exist to improve cellular uptake efficiency of gene-based therapies. This paper highlights advancements in gene therapy research and its application in relation to anti-cancer treatment.
URI: http://hdl.handle.net/1807/7525
Other Identifiers: http://www.bioline.org.br/abstract?id=mj04002
Rights: Copyright 2004 - Malaysian Journal of Medical Science
Appears in Collections:Bioline International Legacy Collection

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