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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/8406

Title: Antibacterial and cytotoxic activity of Brazilian plant extracts - Clusiaceae
Authors: Suffredini, Ivana B.
Paciencia, Mateus L.B.
Nepomuceno, Daniela C.
Younes, Riad N.
Varella, Antonio D.
Keywords: antibacterial - cytotoxicity - Clusiaceae - Amazon rain forest - Brazil
Issue Date: 31-Dec-2006
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 101 Num 3
Abstract: Twelve extracts obtained from nine plants belonging to six different genera of Clusiaceae were analyzed against Gram-negative (Escherichia coli   and Pseudomonas aeruginosa   ) and Gram-positive (Staphylococcus aureus   and Enterococcus faecalis   ) bacteria using the microdilution broth assay. Tovomita aff. longifolia, T. brasiliensis, Clusia columnaris   , Garcinia madruno   , Haploclathra paniculata   , and Caraipa grandifolia   extracts showed significant results against the bacteria. The organic extract obtained from the leaves of T. aff. longifolia showed minimal inhibitory concentration (MIC) = 70 μg/ml and minimal bactericidal concentration (MBC) = 90 μg/ml against E. faecalis and the organic extract made with the stem of C. columnaris showed MIC = 180 μg/ml and MBC = 270 μg/ml against P. aeruginosa. None of the antibacterial extracts showed lethal activity against brine shrimp nauplii. On the other hand, both aqueous and organic extracts obtained from the aerial organs of Vismia guianensis   that were cytotoxic to brine shrimp nauplii did not show a significant antibacterial activity in the assay.
URI: http://hdl.handle.net/1807/8406
Other Identifiers: http://www.bioline.org.br/abstract?id=oc06051
Rights: Copyright 2006 - Instituto Oswaldo Cruz - Fiocruz
Appears in Collections:Bioline International Legacy Collection

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