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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/8417

Title: Susceptibility of Colombian Plasmodium falciparum isolates to 4-aminoquinolines and the definition of amodiaquine resistance in vitro
Authors: Echeverry, Diego F.
Murillo, Claribel
Restrepo P., Piedad
Osorio, Lyda
Keywords: chloroquine - amodiaquine - N-desethylamodiaquine - in vitro tests
Issue Date: 31-Dec-2006
Publisher: Fundação Oswaldo Cruz, Fiocruz
Citation: Memórias do Instituto Oswaldo Cruz (ISSN: 1678-8060) Vol 101 Num 3
Abstract: There are wide variations in the threshold used to define in vitro resistance of Plasmodium falciparum to amodiaquine (AQ), probably due to differences in methodology and interpretation. In vitro susceptibility data of Colombian P. falciparum strains to AQ and N-desethylamodiaquine is used to illustrate the need to standardized methodologies and compare inhibitory concentrations, instead of resistant/susceptible phenotypes, when studying the mechanisms of resistance to AQ and monitoring drug susceptibility trends in the field.
URI: http://hdl.handle.net/1807/8417
Other Identifiers: http://www.bioline.org.br/abstract?id=oc06062
Rights: Copyright 2006 - Instituto Oswaldo Cruz - Fiocruz
Appears in Collections:Bioline International Legacy Collection

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