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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/8927

Title: Anti-Clastogenic Effects of Citral
Authors: Rabbani, Syed Iman
Devi, Kshama
Zahra, Noor
Keywords: Citral, Antimutagenicity, Micronucleus test, Clastogens
Issue Date: 31-Dec-2005
Publisher: Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
Citation: Iranian Journal of Pharmacology and Therapeutics (ISSN: 1735-2657) Vol 4 Num 1
Abstract: Citral is a major constituent of Cymbopogon citratus   or lemongrass oil. The anti-clastogenic effect of citral (20 mg/kg) was tested against the known mutagens cyclophoshamide, mitomycin-C and nickel metal (NiCl2) in mice. Micronucleus (MN) frequency was evaluated in both bone marrow and peripheral blood erythrocytes. The sampling was done after 24 h, 48 h and 72 h of clastogen treatment. Results show that citral had significantly (p < 0.01) decreased the frequency of MN induced by the three clastogens in bone marrow and peripheral blood erythrocytes.
URI: http://hdl.handle.net/1807/8927
Other Identifiers: http://www.bioline.org.br/abstract?id=pt05007
Rights: Copyright 2005 - Razi Institute for Drug Research (RIDR)
Appears in Collections:Bioline International Legacy Collection

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