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Please use this identifier to cite or link to this item: http://hdl.handle.net/1807/9232

Title: Experimental design optimization for screening relevant free phenolic acids from various preparations used in Burkina Faso folk medicine
Authors: Kiendrebeogo, Martin
Choisnard, Luc
Lamien, Charles E.
Meda, Aline
Wouessidjewe, Denis
Nacoulma, Odile G.
Keywords: Central Composite Face-Centred Design, Chromatographic Response Function, Phenolic acids
Issue Date: 31-Dec-2006
Publisher: African Ethnomedicines Network
Citation: African Journal of Traditional, Complementary and Alternative Medicines (ISSN: 0189-6016) Vol 3 Num 1
Abstract: Experimental design methodology was used to optimize the HPLC separation of various relevant phenolic acids from an artificial mixture. The effect of four characteristic factors of the HPLC procedure on the Chromatographic Response Function was investigated by a Central Composite Face-Centred Design and Multi Linear Regression fitting. The eight phenolic acids were successfully separated. The optimal HPLC setting condition was applied to rapid screening of free phenolic acids from Striga hermonthica (Del.) Benth. (Scrophulariaceae), Guiera senegalensis J. F. Gmel (Combretaceae) and unifloral honey from Acacia sp. (Mimosaceae). None of reference phenolic acid was identified in S. hermonthica extract when some of them were detected in G. senegalensis and honey extracts. This work is considered as a first step for a largest phenolic acids screening from various preparations used in Burkina Faso folk medicine to justify some of their properties or potentialities.
URI: http://hdl.handle.net/1807/9232
Other Identifiers: http://www.bioline.org.br/abstract?id=tc06013
Rights: Copyright 2006 - African Journal Traditional, Complementary and Alternative Medicines
Appears in Collections:Bioline International Legacy Collection

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