|Title: ||Experimental design optimization for screening relevant free phenolic acids from various preparations used in Burkina Faso folk medicine|
|Authors: ||Kiendrebeogo, Martin|
Lamien, Charles E.
Nacoulma, Odile G.
|Keywords: ||Central Composite Face-Centred Design, Chromatographic Response
Function, Phenolic acids|
|Issue Date: ||31-Dec-2006|
|Publisher: ||African Ethnomedicines Network|
|Citation: ||African Journal of Traditional, Complementary and Alternative Medicines (ISSN: 0189-6016) Vol 3 Num 1|
|Abstract: ||Experimental design methodology was used to optimize the HPLC
separation of various relevant phenolic acids from an artificial
mixture. The effect of four characteristic factors of the HPLC
procedure on the Chromatographic Response Function was investigated by
a Central Composite Face-Centred Design and Multi Linear Regression
fitting. The eight phenolic acids were successfully separated. The
optimal HPLC setting condition was applied to rapid screening of free
phenolic acids from Striga hermonthica (Del.) Benth.
(Scrophulariaceae), Guiera senegalensis J. F. Gmel
(Combretaceae) and unifloral honey from Acacia sp. (Mimosaceae). None
of reference phenolic acid was identified in S. hermonthica extract
when some of them were detected in G. senegalensis and honey extracts.
This work is considered as a first step for a largest phenolic acids
screening from various preparations used in Burkina Faso folk medicine
to justify some of their properties or potentialities.|
|Other Identifiers: ||http://www.bioline.org.br/abstract?id=tc06013|
|Rights: ||Copyright 2006 - African Journal Traditional, Complementary and
|Appears in Collections:||Bioline International Legacy Collection|